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Retatrutide (GLP-3)

Price range: $80.00 through $150.00

🛡️Lab-verified purity: 99.76%–99.95% · Third-party tested (HPLC-UV & LC-MS) · View Certificates of Analysis ↓

Retatrutide (GLP-3) — Triple Receptor Agonist Peptide

Retatrutide is a synthetic 39–amino acid peptide studied in metabolic research as a triple agonist of the GIP, GLP-1, and glucagon receptors. It has become a frequent subject of preclinical and laboratory investigation into receptor-signaling and energy-metabolism pathways. Lumen Peptides supplies Retatrutide as a high-purity lyophilized powder intended exclusively for in-vitro research and laboratory study.

About Retatrutide

Retatrutide (also referenced in research as GLP-3 or LY3437943) is engineered to interact simultaneously with three incretin and metabolic receptors, making it a notable tool compound in laboratory studies of multi-receptor signaling. Published research is indexed in the peer-reviewed scientific literature.

Retatrutide Research Applications

In laboratory and preclinical settings, this peptide is studied across several areas of interest:

  • Metabolic & energy-expenditure research — examined in models of energy balance and metabolism.
  • GLP-1 receptor signaling — investigated for incretin-pathway activity in research models.
  • GIP receptor signaling — studied alongside GLP-1 pathways in receptor-interaction research.
  • Glucagon receptor signaling — explored for its role in the triple-agonist mechanism.

These describe areas of ongoing scientific investigation only — this compound is not a therapeutic product and no clinical outcomes are implied.

Specifications

Compound Retatrutide (GLP-3 / LY3437943)
Class GIP / GLP-1 / glucagon triple receptor agonist (39 amino acids)
Molecular formula C221H342N46O68
Molecular weight ~4731.3 g/mol
CAS number 2381089-83-2
Form Lyophilized powder

Reconstitution, Storage & Handling

Supplied as a lyophilized powder, the peptide is typically reconstituted with bacteriostatic or sterile water for laboratory use. Store the sealed lyophilized vial at -20 °C, protected from light and moisture, for long-term stability. After reconstitution, store at 2–8 °C and use within the timeframe defined by your laboratory protocol. Handle using standard laboratory safety practices.

For Research Use Only

This product is intended strictly for laboratory and in-vitro research. It is not for human or veterinary use, consumption, or diagnostic application, and is not a drug, food, or cosmetic. By purchasing, the buyer affirms they are a qualified researcher or institution. Browse our full catalog of research peptides.

Further reading: Retatrutide research guide — what the studies show.

Retatrutide Certificate of Analysis (COA) — Third-Party Lab-Tested

Every batch of Lumen Peptides Retatrutide is independently tested by Freedom Diagnostics (USA). The 10 mg batch is verified at 99.76% and the 20 mg batch at 99.95% HPLC-UV purity, with identity confirmed by LC-MS. View or download each Certificate of Analysis below.

🛡️ Lab Verified · Third-Party Tested
Retatrutide 10 mg Certificate of Analysis – 99.76% HPLC-UV purity, lot 590B4F2, third-party tested by Freedom Diagnostics

Retatrutide 10 mg · COA

99.76% HPLC-UV purity

  • Identity confirmed (LC-MS) — GLP RT
  • Net content — 10.95 mg
  • Appearance — White lyophilized powder
  • Batch / Lot — 590B4F2

↓ View Full COA (PDF)

Tested by Freedom Diagnostics · Proudly tested in the USA · Reported 06/21/2026

For research use only. Not approved for human or veterinary use, diagnostic, therapeutic, or clinical applications. Results are specific to the sample(s) tested.

🛡️ Lab Verified · Third-Party Tested
Retatrutide 20 mg Certificate of Analysis – 99.95% HPLC-UV purity, lot 62J1N81, third-party tested by Freedom Diagnostics

Retatrutide 20 mg · COA

99.95% HPLC-UV purity

  • Identity confirmed (LC-MS) — GLP RT
  • Net content — 22.96 mg
  • Appearance — White lyophilized powder
  • Batch / Lot — 62J1N81

↓ View Full COA (PDF)

Tested by Freedom Diagnostics · Proudly tested in the USA · Reported 06/21/2026

For research use only. Not approved for human or veterinary use, diagnostic, therapeutic, or clinical applications. Results are specific to the sample(s) tested.

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FOR RESEARCH PURPOSES ONLY

All items are marketed solely for laboratory use, chemical analysis, or in a research setting. None of our products are designed for human consumption. Any comments or claims expressed on this site, and the products sold here, have not been approved by the U.S. FDA (U.S. Food and Drug Administration) as an evaluation for their safety, efficacy, or effectiveness. In addition, no claim is being made regarding these products that they will diagnose, treat, cure or prevent any disease.

Lumen Peptides is a chemical supplier. Lumen Peptides does not qualify to be called a compounding pharmacy (or chemical compounding facility) as defined by the federal food drug and cosmetic act in section 503A. Lumen Peptides does not qualify to be called an outsourcing facility as defined by the federal food drug and cosmetic act in Section 503B.